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mouse anti human ic3b antibody  (Bio-Rad)


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    Bio-Rad mouse anti human ic3b antibody
    The second-generation hC3 rats exhibit normal renal function but show signs of glomeruli <t>iC3b</t> deposition. Urine samples were collected from WT and second-generation hC3 rats at 2 and 6 months of age. Urea nitrogen and creatinine levels were measured using a Roche Cobas 6000 analyzer (A-D). Male and female second-generation hC3 rats at 8 months of age were perfused and kidneys were collected to detect iC3b by confocal imaging using an iC3b neoepitope-specific monoclonal antibody, showing some positive signals in the glomeruli (E-H). MDA-MB-231 cells incubated with 10% normal human serum were processed in the identical way to serve as a positive control (I-J). 2nd gen, second generation; Ms IgG, mouse IgG, which was used as the staining negative control.
    Mouse Anti Human Ic3b Antibody, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 91/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/mouse anti human ic3b antibody/product/Bio-Rad
    Average 91 stars, based on 3 article reviews
    mouse anti human ic3b antibody - by Bioz Stars, 2026-05
    91/100 stars

    Images

    1) Product Images from "A second generation of C3 humanized rats for preclinical evaluation of human C3 inhibitors"

    Article Title: A second generation of C3 humanized rats for preclinical evaluation of human C3 inhibitors

    Journal: Blood Vessels, Thrombosis & Hemostasis

    doi: 10.1016/j.bvth.2026.100138

    The second-generation hC3 rats exhibit normal renal function but show signs of glomeruli iC3b deposition. Urine samples were collected from WT and second-generation hC3 rats at 2 and 6 months of age. Urea nitrogen and creatinine levels were measured using a Roche Cobas 6000 analyzer (A-D). Male and female second-generation hC3 rats at 8 months of age were perfused and kidneys were collected to detect iC3b by confocal imaging using an iC3b neoepitope-specific monoclonal antibody, showing some positive signals in the glomeruli (E-H). MDA-MB-231 cells incubated with 10% normal human serum were processed in the identical way to serve as a positive control (I-J). 2nd gen, second generation; Ms IgG, mouse IgG, which was used as the staining negative control.
    Figure Legend Snippet: The second-generation hC3 rats exhibit normal renal function but show signs of glomeruli iC3b deposition. Urine samples were collected from WT and second-generation hC3 rats at 2 and 6 months of age. Urea nitrogen and creatinine levels were measured using a Roche Cobas 6000 analyzer (A-D). Male and female second-generation hC3 rats at 8 months of age were perfused and kidneys were collected to detect iC3b by confocal imaging using an iC3b neoepitope-specific monoclonal antibody, showing some positive signals in the glomeruli (E-H). MDA-MB-231 cells incubated with 10% normal human serum were processed in the identical way to serve as a positive control (I-J). 2nd gen, second generation; Ms IgG, mouse IgG, which was used as the staining negative control.

    Techniques Used: Imaging, Incubation, Positive Control, Staining, Negative Control



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    Image Search Results


    The second-generation hC3 rats exhibit normal renal function but show signs of glomeruli iC3b deposition. Urine samples were collected from WT and second-generation hC3 rats at 2 and 6 months of age. Urea nitrogen and creatinine levels were measured using a Roche Cobas 6000 analyzer (A-D). Male and female second-generation hC3 rats at 8 months of age were perfused and kidneys were collected to detect iC3b by confocal imaging using an iC3b neoepitope-specific monoclonal antibody, showing some positive signals in the glomeruli (E-H). MDA-MB-231 cells incubated with 10% normal human serum were processed in the identical way to serve as a positive control (I-J). 2nd gen, second generation; Ms IgG, mouse IgG, which was used as the staining negative control.

    Journal: Blood Vessels, Thrombosis & Hemostasis

    Article Title: A second generation of C3 humanized rats for preclinical evaluation of human C3 inhibitors

    doi: 10.1016/j.bvth.2026.100138

    Figure Lengend Snippet: The second-generation hC3 rats exhibit normal renal function but show signs of glomeruli iC3b deposition. Urine samples were collected from WT and second-generation hC3 rats at 2 and 6 months of age. Urea nitrogen and creatinine levels were measured using a Roche Cobas 6000 analyzer (A-D). Male and female second-generation hC3 rats at 8 months of age were perfused and kidneys were collected to detect iC3b by confocal imaging using an iC3b neoepitope-specific monoclonal antibody, showing some positive signals in the glomeruli (E-H). MDA-MB-231 cells incubated with 10% normal human serum were processed in the identical way to serve as a positive control (I-J). 2nd gen, second generation; Ms IgG, mouse IgG, which was used as the staining negative control.

    Article Snippet: Sections were incubated overnight at 4°C with mouse anti-human iC3b antibody (1:100 dilution; Neoantigen/Bio-Rad, catalog no. MCA2607) prepared in 1% BSA.

    Techniques: Imaging, Incubation, Positive Control, Staining, Negative Control